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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRF2
All Species:
23.64
Human Site:
S264
Identified Species:
57.78
UniProt:
P14316
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14316
NP_002190.2
349
39354
S264
I
E
G
K
Q
Y
L
S
N
M
G
T
R
G
S
Chimpanzee
Pan troglodytes
XP_517553
349
39322
S264
I
E
G
K
Q
Y
L
S
N
M
G
T
R
G
S
Rhesus Macaque
Macaca mulatta
NP_001129265
349
39337
S264
I
E
G
K
Q
Y
L
S
N
M
G
T
R
G
S
Dog
Lupus familis
XP_848907
349
39363
S264
I
E
G
K
Q
Y
L
S
N
M
G
T
R
S
T
Cat
Felis silvestris
Mouse
Mus musculus
P23906
349
39434
S264
I
E
G
K
Q
Y
L
S
N
M
G
T
R
N
T
Rat
Rattus norvegicus
P23570
328
37046
L241
L
P
E
D
I
M
K
L
F
E
Q
S
E
W
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519249
227
24375
S143
S
V
P
S
D
E
E
S
P
E
P
I
V
S
T
Chicken
Gallus gallus
Q98925
348
39333
S262
I
E
G
K
Q
Y
L
S
N
L
G
M
R
N
T
Frog
Xenopus laevis
NP_001088726
347
39272
T262
G
S
K
E
S
V
R
T
S
S
Q
R
A
P
Y
Zebra Danio
Brachydanio rerio
NP_001008614
155
18098
T70
G
D
K
P
D
P
K
T
W
K
A
N
F
R
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.7
95.1
N.A.
92.5
38.4
N.A.
38.4
83.6
68.1
36
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
100
96.8
N.A.
96.5
55.5
N.A.
48.4
92.5
79.6
40.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
0
N.A.
6.6
73.3
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
13.3
86.6
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
10
0
10
20
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
60
10
10
0
10
10
0
0
20
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% F
% Gly:
20
0
60
0
0
0
0
0
0
0
60
0
0
30
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
60
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
20
60
0
0
20
0
0
10
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
60
10
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
50
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
60
0
0
10
0
20
0
% N
% Pro:
0
10
10
10
0
10
0
0
10
0
10
0
0
10
0
% P
% Gln:
0
0
0
0
60
0
0
0
0
0
20
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
10
60
10
0
% R
% Ser:
10
10
0
10
10
0
0
70
10
10
0
10
0
20
30
% S
% Thr:
0
0
0
0
0
0
0
20
0
0
0
50
0
0
40
% T
% Val:
0
10
0
0
0
10
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _